For research use only. Not for therapeutic Use.
Neticonazole hydrochloride(CAT: M114901) is an imidazole-class antifungal agent with broad-spectrum activity against dermatophytes, yeasts, and other pathogenic fungi. It functions by inhibiting fungal cytochrome P450–dependent 14α-demethylase, an essential enzyme in ergosterol biosynthesis, thereby disrupting cell membrane integrity and inhibiting fungal growth. Neticonazole hydrochloride has been studied primarily for the treatment of superficial mycoses, including tinea and candidiasis. In research settings, it serves as a valuable tool for investigating antifungal mechanisms, resistance pathways, and the pharmacological potential of imidazole derivatives. Its well-characterized activity makes it an important reference compound in infectious disease and antifungal drug development studies.
| CAS Number | 130773-02-3 |
| Synonyms | 1-[(E)-2-methylsulfanyl-1-(2-pentoxyphenyl)ethenyl]imidazole;hydrochloride |
| Molecular Formula | C17H23ClN2OS |
| Purity | ≥95% |
| IUPAC Name | 1-[(E)-2-methylsulfanyl-1-(2-pentoxyphenyl)ethenyl]imidazole;hydrochloride |
| InChI | InChI=1S/C17H22N2OS.ClH/c1-3-4-7-12-20-17-9-6-5-8-15(17)16(13-21-2)19-11-10-18-14-19;/h5-6,8-11,13-14H,3-4,7,12H2,1-2H3;1H/b16-13+; |
| InChIKey | HAHMABKERDVYCH-ZUQRMPMESA-N |
| SMILES | CCCCCOC1=CC=CC=C1C(=CSC)N2C=CN=C2.Cl |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
