Nepsilon-acetyl-L-lysine-d8

• CAT Number: I043938
• Molecular Formula: C8H8D8N2O3
• Molecular Weight: 196.27
• Purity: ≥95%
• Synonyms: (2S)-6-acetamido-2-amino-3,3,4,4,5,5,6,6-octadeuteriohexanoic acid
• InChI: InChI=1S/C8H16N2O3/c1-6(11)10-5-3-2-4-7(9)8(12)13/h7H,2-5,9H2,1H3,(H,10,11)(H,12,13)/t7-/m0/s1/i2D2,3D2,4D2,5D2
• InChIKey: DTERQYGMUDWYAZ-IYVSXXDFSA-N
• SMILES: [2H]C([2H])([C@@H](C(=O)O)N)C([2H])([2H])C([2H])([2H])C([2H])([2H])NC(=O)C

Nepsilon-acetyl-L-lysine-d8（Cat No.:I043938）is a stable isotope-labeled analog of Nepsilon-acetyl-L-lysine, featuring eight deuterium atoms for enhanced detection in mass spectrometry-based analyses. It serves as an essential internal standard for quantifying acetylated lysine residues in proteomics and metabolomics studies. This compound aids in investigating protein acetylation, a key post-translational modification regulating gene expression, enzyme activity, and cellular signaling. Nepsilon-acetyl-L-lysine-d8 is widely used in epigenetics research to monitor histone modifications and assess lysine acetyltransferase and deacetylase activity, contributing to a deeper understanding of chromatin dynamics and regulatory protein function.