Nelistotug

• CAT Number: I040381
• CAS Number: 2645437-82-5
• Purity: ≥95%

Nelistotug(CAT: I040381) (also known as GSK‑6097608) is a fully human IgG1κ monoclonal antibody targeting CD96, an immune checkpoint receptor on T cells and natural killer cells. By blocking CD96–CD155 interactions, Nelistotug restores T and NK cell effector activity, reversing immune suppression within tumor microenvironments. It is currently in Phase II clinical trials, evaluating its efficacy in solid tumors such as non‑small cell lung cancer and head and neck carcinoma. Preclinical and early clinical data show enhanced anti‑tumor immune responses and a generally favorable safety profile. Supplied at high purity, Nelistotug is ideal for advanced immuno‑oncology and checkpoint inhibitor research.