Necroptosis-IN-1（Cat No.:I044512）is a potent and selective small-molecule inhibitor of necroptosis, a programmed form of inflammatory cell death distinct from apoptosis. It primarily targets key proteins in the necroptotic pathway, such as RIPK1 or RIPK3, disrupting their phosphorylation and downstream signaling that leads to membrane rupture and inflammation. Necroptosis-IN-1 is widely used in research to explore the role of necroptosis in various pathological conditions, including neurodegeneration, ischemia-reperfusion injury, and inflammatory diseases. Its specificity and effectiveness make it a valuable tool for investigating cell death mechanisms and potential therapeutic interventions.