NE-100 hydrochloride

• CAT Number: R032408
• CAS Number: 149409-57-4
• Molecular Formula: C23H34ClNO2
• Molecular Weight: 391.97
• Purity: ≥95%
• Synonyms: N-[2-[4-methoxy-3-(2-phenylethoxy)phenyl]ethyl]-N-propylpropan-1-amine;hydrochloride
• InChI: InChI=1S/C23H33NO2.ClH/c1-4-15-24(16-5-2)17-13-21-11-12-22(25-3)23(19-21)26-18-14-20-9-7-6-8-10-20;/h6-12,19H,4-5,13-18H2,1-3H3;1H
• InChIKey: ZHGMDXSHODHWHV-UHFFFAOYSA-N
• SMILES: CCCN(CCC)CCC1=CC(=C(C=C1)OC)OCCC2=CC=CC=C2.Cl

NE-100 hydrochloride（Cat No.:R032408）is a potent and selective antagonist of the sigma-1 receptor, a chaperone protein involved in modulating calcium signaling, neuroprotection, and cellular stress responses. Widely used in neuropharmacology, NE-100 helps elucidate sigma-1 receptor roles in pain, addiction, depression, and neurodegenerative diseases. By blocking this receptor, NE-100 disrupts its interaction with various ion channels and signaling proteins, aiding the study of neuronal excitability and survival mechanisms. Its specificity makes it a valuable tool for investigating sigma-1 receptor-targeted therapeutic strategies in central nervous system disorders and cancer research.