For research use only. Not for therapeutic Use.
NCGC00029283（Cat No.:I033099）is a small-molecule inhibitor known for its selective activity against the TRPV1 (transient receptor potential vanilloid 1) ion channel, a key mediator of pain, inflammation, and thermal sensation. By antagonizing TRPV1, NCGC00029283 effectively reduces calcium influx and neuronal excitability, making it a useful tool in pain research and sensory neuroscience. It has been utilized in studies exploring analgesic pathways and chronic pain conditions. This compound supports the development of non-opioid pain therapeutics and is ideal for investigating TRPV1-related signaling in both inflammatory and neuropathic pain models.
| CAS Number | 714240-31-0 |
| Synonyms | 3-[5-(4-fluorophenyl)-1,2,4-oxadiazol-3-yl]-6-methoxy-1H-quinolin-2-one |
| Molecular Formula | C18H12FN3O3 |
| Purity | ≥95% |
| IUPAC Name | 3-[5-(4-fluorophenyl)-1,2,4-oxadiazol-3-yl]-6-methoxy-1H-quinolin-2-one |
| InChI | InChI=1S/C18H12FN3O3/c1-24-13-6-7-15-11(8-13)9-14(17(23)20-15)16-21-18(25-22-16)10-2-4-12(19)5-3-10/h2-9H,1H3,(H,20,23) |
| InChIKey | FJQADEHMIMENRE-UHFFFAOYSA-N |
| SMILES | COC1=CC2=C(C=C1)NC(=O)C(=C2)C3=NOC(=N3)C4=CC=C(C=C4)F |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
