NaPi2b-IN-2

• CAT Number: I043851
• CAS Number: 2227445-31-8
• Molecular Formula: C41H47ClF3N5O5S
• Molecular Weight: 814.36
• Purity: ≥95%
• Synonyms: 4-[2-[[3-[[3-[1-[4-chloro-3-(trifluoromethyl)phenyl]pyrazole-4-carbonyl]-6,6-dimethyl-5,7-dihydro-4H-1-benzothiophen-2-yl]carbamoyl]phenyl]methyl-pentan-3-ylamino]ethyl-methylamino]-4-oxobutanoic acid
• InChI: InChI=1S/C41H47ClF3N5O5S/c1-6-28(7-2)49(18-17-48(5)34(51)13-14-35(52)53)23-25-9-8-10-26(19-25)38(55)47-39-36(30-15-16-40(3,4)21-33(30)56-39)37(54)27-22-46-50(24-27)29-11-12-32(42)31(20-29)41(43,44)45/h8-12,19-20,22,24,28H,6-7,13-18,21,23H2,1-5H3,(H,47,55)(H,52,53)
• InChIKey: IHCQIEZWVTZYDU-UHFFFAOYSA-N
• SMILES: CCC(CC)N(CCN(C)C(=O)CCC(=O)O)CC1=CC(=CC=C1)C(=O)NC2=C(C3=C(S2)CC(CC3)(C)C)C(=O)C4=CN(N=C4)C5=CC(=C(C=C5)Cl)C(F)(F)F

NaPi2b-IN-2（Cat No.:I043851）is a selective small molecule inhibitor that targets the sodium-dependent phosphate transporter NaPi2b, which is involved in phosphate transport across cell membranes. This transporter is overexpressed in certain cancer cells, making NaPi2b-IN-2 a promising candidate for cancer research. By inhibiting NaPi2b, this compound may disrupt the phosphate uptake required for tumor growth and survival, potentially leading to reduced tumor proliferation and metastasis. NaPi2b-IN-2 is being explored in preclinical studies to assess its effectiveness as a targeted therapy for cancers that express NaPi2b.