Naphthyridine-azaquinolone is a novel repeat-structure-specific DNA ligand, specifically binding slipped-CAG DNA intermediates of expansion mutations.
| Catalog Number | I033041 |
| CAS Number | 500722-22-5 |
| Synonyms | Naphthyridine-azaquinolone; Npt-Azq; |
| Molecular Formula | C24H25N7O3 |
| Purity | 96% |
| Solubility | Soluble in DMSO |
| Appearance | Solid powder |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| IUPAC Name | 3-[[3-[(7-Methyl-1,8-naphthyridin-2-yl)amino]-3-oxopropyl]amino]-N-[(7-oxo-8H-1,8-naphthyridin-2-yl)methyl]propanamide |
| InChI | InChI=1S/C24H25N7O3/c1-15-2-3-16-5-8-19(30-23(16)27-15)29-22(34)11-13-25-12-10-20(32)26-14-18-7-4-17-6-9-21(33)31-24(17)28-18/h2-9,25H,10-14H2,1H3,(H,26,32)(H,28,31,33)(H,27,29,30,34) |
| InChIKey | BWINWCKASXYPFA-UHFFFAOYSA-N |
| SMILES | O=C(NCC1=NC2=C(C=CC(N2)=O)C=C1)CCNCCC(NC3=NC4=NC(C)=CC=C4C=C3)=O |
| Documentation | CoA |
