For research use only. Not for therapeutic Use.
Naltrexone hydrochloride（Cat No.:A001156）is an opioid antagonist with the molecular formula C20H24ClNO4, primarily used to manage alcohol dependence and prevent relapse in opioid addiction. It works by competitively binding to opioid receptors without activating them, effectively blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Administered orally or via long-acting intramuscular injection, naltrexone is non-addictive and does not cause physical dependence. It is typically part of a comprehensive treatment plan that includes counseling. Common side effects include nausea, headache, fatigue, and liver function changes, requiring periodic monitoring during therapy.
| CAS Number | 16676-29-2 |
| Synonyms | NA |
| Molecular Formula | C20H23NO4 • HCl |
| Purity | ≥95% |
| Documentation | |
| Target | opioid receptor |
| Storage | 3 years -20C powder |
| IUPAC Name | (4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one;hydrochloride |
| InChI | InChI=1S/C20H23NO4.ClH/c22-13-4-3-12-9-15-20(24)6-5-14(23)18-19(20,16(12)17(13)25-18)7-8-21(15)10-11-1-2-11;/h3-4,11,15,18,22,24H,1-2,5-10H2;1H/t15-,18+,19+,20-;/m1./s1 |
| InChIKey | RHBRMCOKKKZVRY-ITLPAZOVSA-N |
| SMILES | C1CC1CN2CC[C@]34[C@@H]5C(=O)CC[C@]3([C@H]2CC6=C4C(=C(C=C6)O)O5)O.Cl |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
