NAD+

• CAT Number: A000315
• CAS Number: 53-84-9
• Molecular Formula: C21H27N7O14P2
• Molecular Weight: 663.4
• Purity: ≥95%
• Storage: 3 years -20C powder
• IUPAC Name: [[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2R,3S,4R,5R)-5-(3-carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphate
• InChI: InChI=1S/C21H27N7O14P2/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(32)14(30)11(41-21)6-39-44(36,37)42-43(34,35)38-5-10-13(29)15(31)20(40-10)27-3-1-2-9(4-27)18(23)33/h1-4,7-8,10-11,13-16,20-21,29-32H,5-6H2,(H5-,22,23,24,25,33,34,35,36,37)/t10-,11-,13-,14-,15-,16-,20-,21-/m1/s1
• InChIKey: BAWFJGJZGIEFAR-NNYOXOHSSA-N
• SMILES: C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)([O-])OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

NAD+ (CAS 53-84-9) is a coenzyme composed of ribosylnicotinamide 5/'-diphosphate coupled to adenosine 5/'-phosphate by pyrophosphate linkage. It acts as an oxidizing agent, accepting electrons from other molecules while being converted to its reduced form, NADH. NAD+ is also essential for the activity of several enzymes, including poly(ADP)-<wbr style="font-size: 16px; box-sizing: border-box; font-family: Lato, "Lucida Grande", "Lucida Sans Unicode", "Lucida Sans", Geneva, Verdana, sans-serif; font-variant-ligatures: normal; orphans: 2; widows: 2;" />ribose polymerases and cADP-<wbr style="font-size: 16px; box-sizing: border-box; font-family: Lato, "Lucida Grande", "Lucida Sans Unicode", "Lucida Sans", Geneva, Verdana, sans-serif; font-variant-ligatures: normal; orphans: 2; widows: 2;" />ribose synthases.

Reference

1.Acrylamide, Phos Binding Reagent, Cell Counting Kit, and SYBR Safe DNA Gel Stain. "NAD."

2.Houtkooper, R.H., Cantó, C., Wanders, R.J., et al. The secret life of NAD+: An old metabolite controlling new metabolic signaling pathways. Endocr. Rev. 31(2),194-223 (2010).