N1-Boc-N4-Fmoc-piperazine-2-carboxylic acid（Cat No.:R038316）is a bifunctionally protected piperazine derivative, widely used in peptide synthesis and medicinal chemistry. The molecule contains a piperazine ring substituted with a carboxylic acid at the 2-position, an N-Boc (tert-butoxycarbonyl) group on one nitrogen, and an N-Fmoc (9-fluorenylmethyloxycarbonyl) group on the other. These orthogonal protecting groups allow for selective deprotection and stepwise functionalization, making it ideal for solid-phase synthesis and fragment-based drug design. Its rigid, nitrogen-rich structure offers conformational control and solubility, supporting its use in developing peptidomimetics and structurally defined bioactive molecules.