N-tert-Butoxycarbonyl-L-tert-leucine

• CAT Number: R057324
• CAS Number: 62965-35-9
• Molecular Formula: C11H21NO4
• Molecular Weight: 231.29
• Purity: ≥95%
• Synonyms: (2S)-2-(tert-Butoxycarbonylamino)-3,3-dimethylbutanoic Acid; (S)-2-(((tert-Butoxy)carbonyl)amino)-3,3-dimethylbutanoic Acid; (S)-2-tert-Butoxycarbonylamino-3,3-dimethylbutyric Acid; N-Boc-L-tert-leucine; N-tert-Butoxycarbonyl-L-tert-butylglycine
• Storage: -20°C
• IUPAC Name: (2S)-3,3-dimethyl-2-[(2-methylpropan-2-yl)oxycarbonylamino]butanoic acid
• InChI: InChI=1S/C11H21NO4/c1-10(2,3)7(8(13)14)12-9(15)16-11(4,5)6/h7H,1-6H3,(H,12,15)(H,13,14)/t7-/m1/s1
• InChIKey: LRFZIPCTFBPFLX-SSDOTTSWSA-N
• SMILES: CC(C)(C)[C@@H](C(=O)O)NC(=O)OC(C)(C)C

N-tert-Butoxycarbonyl-L-tert-leucine (Cat No.:R057324) is a protected amino acid derivative widely used in peptide synthesis. It features a bulky tert-butyl side chain and a Boc (tert-butoxycarbonyl) protecting group on the amino function, providing steric hindrance and stability under basic conditions. With the molecular formula C₁₁H₂₁NO₄, it serves as a building block in solid-phase peptide synthesis (SPPS), facilitating selective deprotection and coupling. Boc-L-tert-leucine is favored for its hydrophobic profile and structural rigidity, contributing to improved peptide folding and biological stability in drug development, combinatorial chemistry, and biochemical research applications.