N-(Propargyl-PEG4)-biocytin

• CAT Number: I014538
• CAS Number: 2055042-71-0
• Molecular Formula: C28H46N4O9S
• Molecular Weight: 614.75
• Purity: ≥95%
• Synonyms: (2S)-6-[5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoylamino]-2-[3-[2-[2-(2-prop-2-ynoxyethoxy)ethoxy]ethoxy]propanoylamino]hexanoic acid
• InChI: InChI=1S/C28H46N4O9S/c1-2-12-38-14-16-40-18-19-41-17-15-39-13-10-25(34)30-21(27(35)36)7-5-6-11-29-24(33)9-4-3-8-23-26-22(20-42-23)31-28(37)32-26/h1,21-23,26H,3-20H2,(H,29,33)(H,30,34)(H,35,36)(H2,31,32,37)/t21-,22-,23-,26-/m0/s1
• InChIKey: IPPRUAQKQUEPCX-HZLPDVBGSA-N
• SMILES: C#CCOCCOCCOCCOCCC(=O)N[C@@H](CCCCNC(=O)CCCC[C@H]1[C@@H]2[C@H](CS1)NC(=O)N2)C(=O)O

N-(Propargyl-PEG4)-biocytin（Cat No.:I014538）is a versatile biotinylated probe that integrates a propargyl group for copper-catalyzed azide–alkyne cycloaddition (click chemistry) with a PEG4 spacer and a biocytin moiety. The biotin component provides high-affinity binding to streptavidin or avidin systems, enabling efficient capture, detection, and purification. The PEG4 linker imparts hydrophilicity, flexibility, and reduced steric hindrance, ensuring optimal solubility and reactivity in aqueous or mixed environments. This multifunctional reagent is widely employed in chemical biology, proteomics, imaging, and drug discovery for site-specific labeling, enrichment, and molecular interaction studies.