N-Octanoyl-L-homoserine lactone

• CAT Number: M103638
• CAS Number: 147852-84-4
• Molecular Formula: C12H21NO3
• Molecular Weight: 227.30
• Purity: ≥95%
• Synonyms: N-[(3S)-2-oxooxolan-3-yl]octanamide
• InChI: InChI=1S/C12H21NO3/c1-2-3-4-5-6-7-11(14)13-10-8-9-16-12(10)15/h10H,2-9H2,1H3,(H,13,14)/t10-/m0/s1
• InChIKey: JKEJEOJPJVRHMQ-JTQLQIEISA-N
• SMILES: CCCCCCCC(=O)N[C@H]1CCOC1=O

N-Octanoyl-L-homoserine lactone (Cat No.:M103638) is a quorum-sensing signaling molecule belonging to the N-acyl homoserine lactone (AHL) family. Produced by Gram-negative bacteria, it regulates population-dependent gene expression, controlling processes such as biofilm formation, virulence factor production, and symbiotic interactions. Structurally, it features a homoserine lactone ring linked to an octanoyl side chain, conferring specificity in bacterial communication networks. In microbiology research, C8-HSL is widely used to study quorum-sensing pathways, bacterial community behaviors, and host–pathogen interactions, providing insights into antimicrobial development and strategies to disrupt pathogenic signaling systems.