N-Nitro-1,2,3,4-tetradehydro Argatroban

• CAT Number: R056521
• CAS Number: 74874-10-5
• Molecular Formula: C23H31N7O7S
• Molecular Weight: 549.60
• Purity: ≥95%
• Synonyms: (2R,4R)-1-[(2S)-5-[[Imino(nitroamino)methyl]amino]-2-[[(3-methyl-8-quinolinyl)sulfonyl]amino]-1-oxopentyl]-4-methyl-2-piperidinecarboxylic Acid; [2R-[1(S*),2α,4β]]-1-[5-[[Imino(nitroamino)methyl]amino]-2-[[(3-methyl-8-quinolinyl)sulfonyl]amino]-1-oxo
• Storage: Desiccate at -20C
• IUPAC Name: (2R,4R)-1-[(2S)-5-[[amino(nitramido)methylidene]amino]-2-[(3-methylquinolin-8-yl)sulfonylamino]pentanoyl]-4-methylpiperidine-2-carboxylic acid
• InChI: InChI=1S/C23H31N7O7S/c1-14-8-10-29(18(12-14)22(32)33)21(31)17(6-4-9-25-23(24)27-30(34)35)28-38(36,37)19-7-3-5-16-11-15(2)13-26-20(16)19/h3,5,7,11,13-14,17-18,28H,4,6,8-10,12H2,1-2H3,(H,32,33)(H3,24,25,27)/t14-,17+,18-/m1/s1
• InChIKey: XBDLKMBSCAVLDV-FHLIZLRMSA-N
• SMILES: C[C@@H]1CCN([C@H](C1)C(=O)O)C(=O)[C@H](CCCN=C(N)N[N+](=O)[O-])NS(=O)(=O)C2=CC=CC3=C2N=CC(=C3)C

N-Nitro-1,2,3,4-tetradehydro Argatroban（Cat No.:R056521）is a synthetic derivative of argatroban, a direct thrombin inhibitor used as an anticoagulant. This modified compound includes a nitro group and unsaturated bonds in the tetra-dehydro region, potentially altering its binding affinity and pharmacokinetic profile. It is primarily used in research to study thrombin inhibition, anticoagulant mechanisms, and structure-activity relationships of argatroban analogs. The nitro substitution may enhance selectivity or metabolic stability, offering insights into novel anticoagulant drug design. It is not approved for clinical use and is intended for laboratory and experimental applications only.