N-Methylnuciferine

• CAT Number: R046761
• CAS Number: 754919-24-9
• Molecular Formula: C20H24NO2
• Molecular Weight: 345.86
• Purity: ≥95%
• Synonyms: (6aR)-1,2-dimethoxy-6,6-dimethyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-6-ium
• InChI: InChI=1S/C20H24NO2/c1-21(2)10-9-14-12-17(22-3)20(23-4)19-15-8-6-5-7-13(15)11-16(21)18(14)19/h5-8,12,16H,9-11H2,1-4H3/q+1/t16-/m1/s1
• InChIKey: NJSAZXBJMATEKS-MRXNPFEDSA-N
• SMILES: C[N+]1(CCC2=CC(=C(C3=C2C1CC4=CC=CC=C43)OC)OC)C

N-Methylnuciferine(CAT: R046761) is an aporphine alkaloid derivative structurally related to nuciferine, a major bioactive compound from Nelumbo nucifera (lotus). As a naturally occurring alkaloid, it exhibits diverse pharmacological properties, including anti-inflammatory, antioxidant, and neuroactive effects. Preliminary studies suggest it may influence neurotransmitter systems, making it of interest in neuropharmacology and mental health research. The addition of a methyl group modifies its solubility and receptor-binding characteristics compared to nuciferine, offering insight into structure–activity relationships among aporphine alkaloids. N-Methylnuciferine is a valuable reference standard for natural product chemistry, pharmacognosy, and drug discovery targeting neurological and inflammatory disorders.