N-Mal-N-bis(PEG4-NH-Boc)

• CAT Number: I015890
• CAS Number: 2128735-27-1
• Molecular Formula: C37H66N4O15
• Molecular Weight: 806.94
• Purity: ≥95%
• Synonyms: tert-butyl N-[2-[2-[2-[2-[2-[3-(2,5-dioxopyrrol-1-yl)propanoyl-[2-[2-[2-[2-[2-[(2-methylpropan-2-yl)oxycarbonylamino]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]amino]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]carbamate
• InChI: InChI=1S/C37H66N4O15/c1-36(2,3)55-34(45)38-10-15-47-19-23-51-27-29-53-25-21-49-17-13-40(31(42)9-12-41-32(43)7-8-33(41)44)14-18-50-22-26-54-30-28-52-24-20-48-16-11-39-35(46)56-37(4,5)6/h7-8H,9-30H2,1-6H3,(H,38,45)(H,39,46)
• InChIKey: VQIBCVFZJBEFLP-UHFFFAOYSA-N
• SMILES: CC(C)(C)OC(=O)NCCOCCOCCOCCOCCN(CCOCCOCCOCCOCCNC(=O)OC(C)(C)C)C(=O)CCN1C(=O)C=CC1=O

N-Mal-N-bis(PEG4-NH-Boc)（Cat No.:I015890）is a heterobifunctional PEG derivative featuring a maleimide group and two Boc-protected amines, each connected through PEG₄ linkers. The maleimide moiety enables selective conjugation with thiol groups under mild physiological conditions, forming stable thioether bonds. The Boc-protected amines can be deprotected to yield reactive primary amines, suitable for further coupling with activated esters or carboxyl groups. The PEG₄ chains improve solubility, flexibility, and biocompatibility while minimizing steric hindrance. This versatile reagent is ideal for bioconjugation, crosslinking, nanoparticle functionalization, and advanced drug delivery system design.