N-FMOC-L-phenylalanine

• CAT Number: R040020
• CAS Number: 35661-40-6
• Molecular Formula: C24H21NO4
• Molecular Weight: 387.44
• Purity: ≥95%
• Synonyms: N-9-Fluorenylmethoxycarbonyl-L-phenylalanine; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-phenylalanine; NSC 334293
• Storage: Store at RT
• IUPAC Name: (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-phenylpropanoic acid
• InChI: InChI=1S/C24H21NO4/c26-23(27)22(14-16-8-2-1-3-9-16)25-24(28)29-15-21-19-12-6-4-10-17(19)18-11-5-7-13-20(18)21/h1-13,21-22H,14-15H2,(H,25,28)(H,26,27)/t22-/m0/s1
• InChIKey: SJVFAHZPLIXNDH-QFIPXVFZSA-N
• SMILES: C1=CC=C(C=C1)CC(C(=O)O)NC(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24

N-FMOC-L-phenylalanine (Cat No.: R040020) is a protected amino acid derivative commonly used in solid-phase peptide synthesis (SPPS). The FMOC (9-fluorenylmethyloxycarbonyl) group protects the amino terminus of L-phenylalanine, allowing for selective coupling during peptide chain elongation. Its aromatic side chain contributes to hydrophobic interactions and structural stability in peptides and proteins. Upon completion of synthesis, the FMOC group is removed under mild basic conditions. N-FMOC-L-phenylalanine is essential in automated peptide synthesis protocols and is intended for research and laboratory use only.