N-Fmoc-7-methyl-L-tryptophan

• CAT Number: L013324
• CAS Number: 1808268-53-2
• Molecular Formula: C27H24N2O4
• Molecular Weight: 440.50
• Purity: ≥95%
• IUPAC Name: (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(7-methyl-1H-indol-3-yl)propanoic acid
• InChI: InChI=1S/C27H24N2O4/c1-16-7-6-12-18-17(14-28-25(16)18)13-24(26(30)31)29-27(32)33-15-23-21-10-4-2-8-19(21)20-9-3-5-11-22(20)23/h2-12,14,23-24,28H,13,15H2,1H3,(H,29,32)(H,30,31)/t24-/m0/s1
• InChIKey: LIHWPPTURGLCAT-DEOSSOPVSA-N
• SMILES: CC1=C2C(=CC=C1)C(=CN2)C[C@@H](C(=O)O)NC(=O)OCC3C4=CC=CC=C4C5=CC=CC=C35

N-Fmoc-7-methyl-L-tryptophan（Cat No.:L013324）is a protected, non-canonical amino acid derived from L-tryptophan, featuring a methyl group at the 7-position of the indole ring and an N-terminal fluorenylmethyloxycarbonyl (Fmoc) group. The Fmoc protection allows its use in solid-phase peptide synthesis (SPPS), enabling the incorporation of modified tryptophan residues into custom peptides. The 7-methyl substitution influences the electronic and steric properties of the indole ring, potentially altering peptide conformation, receptor binding, or metabolic stability. This compound is valuable in medicinal chemistry, peptide drug design, and structure–activity relationship (SAR) studies targeting bioactive peptide analogs.