N-Fluorobenzenesulfonimide

For research use only. Not for therapeutic Use.

  • CAT Number: M116214
  • CAS Number: 133745-75-2
  • Molecular Formula: C12H10FNO4S2
  • Molecular Weight: 315.33
  • Purity: ≥95%
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N-Fluorobenzenesulfonimide (CAT: M116214) is an electrophilic fluorinating reagent with the molecular formula C₆H₅SO₂N(F)SO₂C₆H₅. Appearing as a white to off-white crystalline solid, it is stable, non-hygroscopic, and soluble in common organic solvents such as acetonitrile and dichloromethane. NFSI is widely used in organic synthesis for the selective introduction of fluorine atoms into aromatic, aliphatic, and heterocyclic compounds under mild conditions. Its high reactivity and predictable selectivity make it valuable in pharmaceutical, agrochemical, and material science research. Additionally, NFSI serves as an oxidizing agent and plays a role in asymmetric synthesis, facilitating the development of fluorinated bioactive molecules with enhanced metabolic stability.


CAS Number 133745-75-2
Molecular Formula C12H10FNO4S2
Purity ≥95%
Storage Desiccate at -20C
IUPAC Name N-(benzenesulfonyl)-N-fluorobenzenesulfonamide
InChI InChI=1S/C12H10FNO4S2/c13-14(19(15,16)11-7-3-1-4-8-11)20(17,18)12-9-5-2-6-10-12/h1-10H
InChIKey RLKHFSNWQCZBDC-UHFFFAOYSA-N
SMILES C1=CC=C(C=C1)S(=O)(=O)N(F)S(=O)(=O)C2=CC=CC=C2
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