N-Ethyl-N’-(3-dimethylaminopropyl)carbodimide, Hydrochloride

• CAT Number: R006687
• CAS Number: 25952-53-8
• Molecular Formula: C8H18ClN3
• Molecular Weight: 191.703
• Purity: ≥95%
• Synonyms: (3-Dimethylamino-propyl)-ethyl-carbodiimide Hydrochloride; EDC HCl,; EDC-HC; EDAC; EDCI; Water Soluble Carbodiimide.?
• Storage: -20°C
• IUPAC Name: 3-(ethyliminomethylideneamino)-N,N-dimethylpropan-1-amine;hydrochloride
• InChI: InChI=1S/C8H17N3.ClH/c1-4-9-8-10-6-5-7-11(2)3;/h4-7H2,1-3H3;1H
• InChIKey: FPQQSJJWHUJYPU-UHFFFAOYSA-N
• SMILES: CCN=C=NCCCN(C)C.Cl

N-Ethyl-N’-(3-dimethylaminopropyl)carbodimide, Hydrochloride (Cat.No:R006687) is a water soluble condensing reagent. It is generally utilized as a carboxyl activating agent for amide bonding with primary amines. Additionally, it reacts with phosphate groups. It has been utilized in peptide synthesis, crosslinking proteins to nucleic acids as well as preparation of immunoconjugates.

Reference

1.Powell, Heather M., and Steven T. Boyce. "EDC cross-linking improves skin substitute strength and stability." Biomaterials 27.34 (2006): 5821-5827.
2.Seno, Kunihiko, et al. "Spectrophotometric determination of 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride by flow injection analysis." Analytical Sciences 24.4 (2008): 505-508.