For research use only. Not for therapeutic Use.
N-Desethyl Amodiaquine-d5 Dihydrochloride（Cat No.:M141050）is a deuterated internal standard of N-desethyl amodiaquine, the active metabolite of the antimalarial drug amodiaquine. Labeled with five deuterium atoms, it is ideal for use in LC-MS/MS assays to ensure accurate quantification and pharmacokinetic profiling in biological samples. This compound is crucial for drug metabolism studies, therapeutic drug monitoring, and bioanalytical method validation. The dihydrochloride salt enhances stability and solubility. N-Desethyl Amodiaquine-d5 is extensively employed in malaria research, supporting investigations into drug efficacy, resistance, and optimized treatment strategies.
| CAS Number | 1216894-33-5 |
| Synonyms | 4-[(7-chloroquinolin-4-yl)amino]-2-[(1,1,2,2,2-pentadeuterioethylamino)methyl]phenol;dihydrochloride |
| Molecular Formula | C18H15D5Cl3N3O |
| Purity | ≥95% |
| IUPAC Name | 4-[(7-chloroquinolin-4-yl)amino]-2-[(1,1,2,2,2-pentadeuterioethylamino)methyl]phenol;dihydrochloride |
| InChI | InChI=1S/C18H18ClN3O.2ClH/c1-2-20-11-12-9-14(4-6-18(12)23)22-16-7-8-21-17-10-13(19)3-5-15(16)17;;/h3-10,20,23H,2,11H2,1H3,(H,21,22);2*1H/i1D3,2D2;; |
| InChIKey | BCYBRFGUODDEGH-ZWOCKVCESA-N |
| SMILES | [2H]C([2H])([2H])C([2H])([2H])NCC1=C(C=CC(=C1)NC2=C3C=CC(=CC3=NC=C2)Cl)O.Cl.Cl |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
