N-Des-tetrahydrofuran N-(6,7-Dimethoxy-4,4a-dihydroquinazolin-4-amine) Alfuzosin

• CAT Number: C000144
• CAS Number: 928780-95-4
• Molecular Formula: C24H30N8O4
• Molecular Weight: 494.55
• Purity: ≥95%
• Synonyms: N2-(3-((4-Amino-6,7-dimethoxyquinazolin-2-yl)amino)propyl)-6,7-dimethoxy-N2-methylquinazoline-2,4-diamine; Alfuzosin Impurity G
• Storage: 4°C

N-Des-tetrahydrofuran N-(6,7-Dimethoxy-4,4a-dihydroquinazolin-4-amine) Alfuzosin (CAT: C000144) is a dimer impurity associated with Alfuzosin, a medication used to treat symptoms of benign prostatic hyperplasia (enlarged prostate) and help relax the muscles in the prostate and bladder neck. Impurities like N-Des-tetrahydrofuran N-(6,7-Dimethoxy-4,4a-dihydroquinazolin-4-amine) Alfuzosin need to be closely monitored and controlled during the drug manufacturing process to ensure the purity and safety of the final pharmaceutical product.

Reference

Ramage, A.G., et al.: Eur. J. Pharmacol., 129, 307 (1986); Deering, A.H.,: Brit. J. Clin. Pharmacol., 25, 417 (1988); Priolo, L.D., et al.: Eur. J. Clin. Pharmacol., 35, 25 (1988);