N-Cyclopropyl-4-iodobenzamide

• CAT Number: I040362
• CAS Number: 794539-14-3
• Molecular Formula: C10H10INO
• Molecular Weight: 287.10
• Purity: ≥95%
• Synonyms: N-cyclopropyl-4-iodobenzamide
• InChI: InChI=1S/C10H10INO/c11-8-3-1-7(2-4-8)10(13)12-9-5-6-9/h1-4,9H,5-6H2,(H,12,13)
• InChIKey: PZYDJAWERUKJRG-UHFFFAOYSA-N
• SMILES: C1CC1NC(=O)C2=CC=C(C=C2)I

N-Cyclopropyl-4-iodobenzamide(CAT: I040362) is an aromatic amide compound featuring a 4-iodobenzoyl group bonded to a cyclopropyl-substituted nitrogen. The presence of the iodine atom at the para-position makes this molecule a valuable intermediate for palladium-catalyzed cross-coupling reactions such as Suzuki, Sonogashira, or Heck couplings, enabling the synthesis of more complex aromatic and heteroaromatic systems. Its rigid cyclopropyl moiety imparts conformational constraint, often used in drug design to enhance metabolic stability and receptor selectivity. N-Cyclopropyl-4-iodobenzamide is commonly applied in medicinal chemistry, radiolabeling precursor development, and structure–activity relationship (SAR) studies targeting central nervous system or oncology-related pathways.