N-Chloro Ethyl ThioTEPA

• CAT Number: R030653
• CAS Number: 90877-51-3
• Molecular Formula: C6H13ClN3PS
• Molecular Weight: 225.675
• Purity: ≥95%
• Synonyms: ThioTEPA Chloroethyl Analog; ThioTEPA Chloro Impurity; P,P-Bis(1-aziridinyl)-N-(2-chloroethyl)-phosphinothioic Amide; N,N’-Diethylene-N’’-2-chloroethyl Thiophosphoramide; N-(2-Chloroethyl)-P,P-bisaziridinyl Thiophosphamide
• Storage: Desiccate at RT
• IUPAC Name: N-[bis(aziridin-1-yl)phosphinothioyl]-2-chloroethanamine
• InChI: InChI=1S/C6H13ClN3PS/c7-1-2-8-11(12,9-3-4-9)10-5-6-10/h1-6H2,(H,8,12)
• InChIKey: CJMMENRDBJHRMU-UHFFFAOYSA-N
• SMILES: C1CN1P(=S)(NCCCl)N2CC2

N-Chloro ethyl ThioTEPA is a chlorinated derivative of ThioTEPA, a chemotherapeutic agent used to treat various cancers. This compound incorporates a chloroethyl group, enhancing its reactivity and modifying its pharmacological properties. N-Chloro ethyl ThioTEPA is employed in cancer therapy due to its ability to alkylate DNA, thereby interfering with cell division and inducing cell death in rapidly proliferating cancer cells.

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