N-Butyrylglycine-d2

• CAT Number: I045599
• CAS Number: 1219799-10-6
• Molecular Formula: C6H9D2NO3
• Molecular Weight: 147.17
• Purity: ≥95%
• Synonyms: 2-(butanoylamino)-2,2-dideuterioacetic acid
• InChI: InChI=1S/C6H11NO3/c1-2-3-5(8)7-4-6(9)10/h2-4H2,1H3,(H,7,8)(H,9,10)/i4D2
• InChIKey: WPSSBBPLVMTKRN-APZFVMQVSA-N
• SMILES: CCCC(=O)NCC(=O)O

N-Butyrylglycine-d2 (Cat No.: I045599) is a stable isotope-labeled analog of N-butyrylglycine, a glycine conjugate of butyric acid formed during fatty acid and amino acid metabolism. Incorporating two deuterium atoms, it is primarily used as an internal standard in liquid chromatography–mass spectrometry (LC-MS/MS) assays for accurate quantification in biological samples. N-Butyrylglycine is a recognized biomarker for fatty acid oxidation disorders, particularly short-chain acyl-CoA dehydrogenase (SCAD) deficiency. N-Butyrylglycine-d2 is a valuable tool in metabolomics, clinical diagnostics, and biochemical studies of inherited metabolic diseases.

Reference

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.
[Content Brief]