N-Boc-L-phenylalanine

• CAT Number: R051470
• CAS Number: 13734-34-4
• Molecular Formula: C14H19NO4
• Molecular Weight: 265.31
• Purity: ≥95%
• Synonyms: N-[(1,1-dimethylethoxy)carbonyl]-L-Phenylalanine; tert-Butoxycarbonyl-L-phenylalanine; (2S)-2-((tert-Butoxycarbonyl)amino)-3-phenylpropionic Acid
• Storage: Desiccate at +4C
• IUPAC Name: (2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-phenylpropanoic acid
• InChI: InChI=1S/C14H19NO4/c1-14(2,3)19-13(18)15-11(12(16)17)9-10-7-5-4-6-8-10/h4-8,11H,9H2,1-3H3,(H,15,18)(H,16,17)/t11-/m0/s1
• InChIKey: ZYJPUMXJBDHSIF-NSHDSACASA-N
• SMILES: CC(C)(C)OC(=O)NC(CC1=CC=CC=C1)C(=O)O

N-Boc-L-phenylalanine(CAT: R051470) is a protected form of the essential amino acid L-phenylalanine, featuring a tert-butyloxycarbonyl (Boc) group on the amino functionality. With the molecular formula C₁₄H₁₉NO₄, it is widely used in peptide synthesis to prevent unwanted reactions at the amino site during coupling steps. The Boc group is stable under mildly basic conditions but can be removed under acidic conditions, enabling orthogonal protection strategies. N-Boc-L-phenylalanine is also employed in medicinal chemistry and chemical biology for preparing peptidomimetics, bioactive derivatives, and structure–activity relationship (SAR) studies. Its stability and ease of handling make it a reliable building block for synthetic and pharmaceutical research.