N-Boc-L-cis-4,5-Methanoprolineamide

• CAT Number: R030636
• CAS Number: 361440-67-7
• Molecular Formula: C11H18N2O3
• Molecular Weight: 226.27
• Purity: ≥95%
• Synonyms: tert-Butyl (1S,3S,5S)-3-carbamoyl-2-azabicyclo[3.1.0]hexane-2-carboxylate; (1S,3S,5S)-3-(Aminocarbonyl)-2-azabicyclo[3.1.0]hexane-2-carboxylic Acid 1,1-Dimethylethyl Ester
• Storage: Desiccate at RT
• IUPAC Name: tert-butyl (1S,3S,5S)-3-carbamoyl-2-azabicyclo[3.1.0]hexane-2-carboxylate
• InChI: InChI=1S/C11H18N2O3/c1-11(2,3)16-10(15)13-7-4-6(7)5-8(13)9(12)14/h6-8H,4-5H2,1-3H3,(H2,12,14)/t6-,7-,8-/m0/s1
• InChIKey: VLAGXRRGXCNITB-FXQIFTODSA-N
• SMILES: CC(C)(C)OC(=O)N1[C@H]2C[C@H]2C[C@H]1C(=O)N

N-Boc-L-cis-4,5-Methanoprolineamide（Cat No.:R030636）is a modified amino acid derivative commonly used in peptide synthesis and structural studies. The Boc (tert-butoxycarbonyl) group provides temporary protection for the amine, while the cis-configuration at the 4,5 positions of the proline ring contributes to unique steric and structural features. This compound is utilized in the design of cyclic peptides, particularly those requiring conformational constraints for biological activity or stability. Its structural properties make it valuable in studying protein folding, receptor interactions, and the design of therapeutically relevant molecules.