N-Boc-hydroxylamine

• CAT Number: R045270
• CAS Number: 36016-38-3
• Molecular Formula: C5H11NO3
• Molecular Weight: 133.15
• Purity: ≥95%
• Synonyms: N-Hydroxycarbamic Acid 1,1-Dimethylethyl Ester; Hydroxycarbamic Acid 1,1-Dimethylethyl Ester; Hydroxycarbamic Acid tert-Butyl Ester; 1,1-Dimethylethyl N-Hydroxycarbamate; N-(tert-Butoxycarbonyl)hydroxylamine; N-(tert-Butyloxycarbonyl)hydroxylamine; N
• Storage: Desiccate at RT
• IUPAC Name: tert-butyl N-hydroxycarbamate
• InChI: InChI=1S/C5H11NO3/c1-5(2,3)9-4(7)6-8/h8H,1-3H3,(H,6,7)
• InChIKey: DRDVJQOGFWAVLH-UHFFFAOYSA-N
• SMILES: CC(C)(C)OC(=O)NO

N-Boc-hydroxylamine（Cat No.:R045270）is a protected form of hydroxylamine, where the amino group is shielded by a tert-butoxycarbonyl (Boc) group. This protection enhances its stability and handling in synthetic procedures, particularly in peptide and medicinal chemistry. It serves as a versatile intermediate for introducing hydroxylamine functionalities into molecules and is used in the synthesis of oximes, hydroxamic acids, and other nitrogen-containing compounds. The Boc group can be easily removed under acidic conditions, enabling selective deprotection. N-Boc-hydroxylamine is typically a white crystalline solid, soluble in organic solvents, and sensitive to moisture.