N-Boc-exo-1-aminotropane

• CAT Number: R032205
• CAS Number: 744183-20-8
• Molecular Formula: C₁₂H₂₂N₂O₂
• Molecular Weight: 226.32
• Purity: ≥95%
• Synonyms: exo-3-Amino-8-Boc-8-azabicyclo[3.2.1]octane; 8-N-Boc-3-(exo-amino)-8-azabicyclo[3.2.1]octane
• Storage: Store at -20C
• IUPAC Name: tert-butyl (1R,5S)-3-amino-8-azabicyclo[3.2.1]octane-8-carboxylate
• InChI: InChI=1S/C12H22N2O2/c1-12(2,3)16-11(15)14-9-4-5-10(14)7-8(13)6-9/h8-10H,4-7,13H2,1-3H3/t8?,9-,10+
• InChIKey: NZJKEPNCNBWESN-PBINXNQUSA-N
• SMILES: CC(C)(C)OC(=O)N1[C@@H]2CC[C@H]1CC(C2)N

N-Boc-exo-1-aminotropane(CAT: R032205) is a protected bicyclic amine widely used in the synthesis of neurologically active compounds. Featuring a tropane core with an exo-oriented amino group protected by a tert-butoxycarbonyl (Boc) group, it offers both structural rigidity and synthetic versatility. The Boc protection ensures compatibility with diverse reaction conditions and can be selectively removed under mild acidic treatment. This compound is particularly valuable in medicinal chemistry for developing dopamine transporter inhibitors, anticholinergics, and other central nervous system agents.