N-Boc-dolaproine dicyclohexylamine

• CAT Number: I040506
• CAS Number: 1369427-40-6
• Molecular Formula: C26H48N2O5
• Molecular Weight: 468.67
• Purity: ≥95%
• Synonyms: N-cyclohexylcyclohexanamine;(2R,3R)-3-methoxy-2-methyl-3-[(2S)-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidin-2-yl]propanoic acid
• InChI: InChI=1S/C14H25NO5.C12H23N/c1-9(12(16)17)11(19-5)10-7-6-8-15(10)13(18)20-14(2,3)4;1-3-7-11(8-4-1)13-12-9-5-2-6-10-12/h9-11H,6-8H2,1-5H3,(H,16,17);11-13H,1-10H2/t9-,10+,11-;/m1./s1
• InChIKey: PKZALTWOMMNNOL-QJQMQQLTSA-N
• SMILES: CC(C(C1CCCN1C(=O)OC(C)(C)C)OC)C(=O)O.C1CCC(CC1)NC2CCCCC2

N-Boc-dolaproine dicyclohexylamine(CAT: I040506) is a protected amino acid derivative of dolaproine, a key residue in the marine-derived pentapeptide Dolastatin 10 (HY-15580). This compound includes a dicyclohexylamine salt form and a Boc-protecting group, making it suitable for peptide synthesis and analog development. As part of Dolastatin 10’s structure, dolaproine contributes to the potent inhibition of tubulin polymerization and mitotic arrest, leading to strong anticancer activity. N-Boc-dolaproine dicyclohexylamine is ideal for constructing cytotoxic peptide-based therapeutics, including antibody-drug conjugates (ADCs). Supplied in high purity, it supports advanced research in oncology, peptide chemistry, and targeted drug development.