N-Boc-4-piperidinmethanol

• CAT Number: R020245
• CAS Number: 123855-51-6
• Molecular Formula: C11H21NO3
• Molecular Weight: 215.293
• Purity: ≥95%
• Synonyms: 1,1-Dimethylethyl 4-(Hydroxymethyl)-1-piperidinecarboxylate; 1-(tert-Butoxycarbonyl)-4-(hydroxymethyl)piperidine; 1-(tert-Butoxycarbonyl)-4-piperidinemethanol; 1-Boc-4-Hydroxymethylpiperidine; 4-(Hydroxymethyl)-1-piperidinecarboxylic Acid 1,1-Dimethy
• Target: Cholinesterase (ChE)
• Storage: -20°C
• IUPAC Name: tert-butyl 4-(hydroxymethyl)piperidine-1-carboxylate
• InChI: InChI=1S/C11H21NO3/c1-11(2,3)15-10(14)12-6-4-9(8-13)5-7-12/h9,13H,4-8H2,1-3H3
• InChIKey: CTEDVGRUGMPBHE-UHFFFAOYSA-N
• SMILES: CC(C)(C)OC(=O)N1CCC(CC1)CO

N-Boc-4-piperidinmethanol(CAT: R020245) is a protected piperidine derivative featuring a tert-butoxycarbonyl (Boc) group on the nitrogen and a hydroxymethyl group at the 4-position. This versatile intermediate is commonly used in peptidomimetic synthesis, medicinal chemistry, and heterocyclic compound development. The Boc group offers acid-labile protection for controlled deprotection, while the hydroxyl group enables further functionalization such as esterification or oxidation. Its conformational flexibility and reactive sites make it suitable for building pharmacologically active molecules, including CNS agents and enzyme inhibitors. N-Boc-4-piperidinmethanol is also used in solid-phase synthesis and structure–activity relationship (SAR) studies in drug discovery.