N-Boc-4-Hydroxypiperidine

• CAT Number: R059222
• CAS Number: 109384-19-2
• Molecular Formula: C10H19NO3
• Molecular Weight: 201.27
• Purity: ≥95%
• Synonyms: 1,1-Dimethylethyl 4-Hydroxypiperidine-1-carboxylate; 1-(tert-Butoxycarbonyl)-4-hydroxypiperidine; 1-(tert-Butyloxycarbonyl)piperidin-4-ol; 1-Boc-4-Hydroxypiperidine; 1-Boc-piperidin-4-ol; 1-tert-Butoxycarbonyl-4-piperidinol; 1-tert-Butyloxycarbonyl-4
• Storage: Store at -20C
• IUPAC Name: tert-butyl 4-hydroxypiperidine-1-carboxylate
• InChI: InChI=1S/C10H19NO3/c1-10(2,3)14-9(13)11-6-4-8(12)5-7-11/h8,12H,4-7H2,1-3H3
• InChIKey: PWQLFIKTGRINFF-UHFFFAOYSA-N
• SMILES: CC(C)(C)OC(=O)N1CCC(CC1)O

N-Boc-4-hydroxypiperidine（Cat No.:R059222）is a protected piperidine derivative with the molecular formula C10H19NO3. It features a piperidine ring bearing a hydroxyl group at the 4-position and a tert-butoxycarbonyl (Boc) protecting group on the nitrogen. This compound appears as a white to off-white crystalline solid and is widely used as a building block in medicinal chemistry and pharmaceutical synthesis. The Boc group stabilizes the nitrogen during multi-step reactions, allowing selective transformations at other positions. N-Boc-4-hydroxypiperidine is especially valuable in synthesizing CNS-active agents, heterocycles, and intermediates for drug development and combinatorial libraries.