N-(BOC)-4-fluoroindole-2-boronic acid

• CAT Number: R072815
• CAS Number: 1000068-25-6
• PubChem Substance ID: 44118245
• Molecular Formula: C13H15BFNO4
• Molecular Weight: 279.07
• Purity: ≥95%
• IUPAC Name: [4-fluoro-1-[(2-methylpropan-2-yl)oxycarbonyl]indol-2-yl]boronic acid
• InChI: InChI=1S/C13H15BFNO4/c1-13(2,3)20-12(17)16-10-6-4-5-9(15)8(10)7-11(16)14(18)19/h4-7,18-19H,1-3H3
• InChIKey: GIHZCAVQMVZATP-UHFFFAOYSA-N
• SMILES: B(C1=CC2=C(N1C(=O)OC(C)(C)C)C=CC=C2F)(O)O

N-(BOC)-4-fluoroindole-2-boronic acid（Cat No.:R072815）is a boronic acid derivative featuring a 4-fluoroindole core with a boronic acid group at the 2-position and a BOC (tert-butoxycarbonyl) protecting group on the nitrogen. This multifunctional compound is widely used in medicinal and synthetic chemistry, particularly in Suzuki-Miyaura cross-coupling reactions for constructing carbon–carbon bonds. The indole scaffold and boronic acid functionality make it valuable in the development of pharmaceuticals, especially kinase inhibitors and CNS-targeted agents. Its BOC group enhances stability and enables selective deprotection in multi-step synthesis.