N-(Azido-PEG3)-N-(PEG2-NH-Boc)-PEG3-acid

• CAT Number: I016534
• CAS Number: 2183440-74-4
• Molecular Formula: C29H55N5O13
• Molecular Weight: 681.77
• Purity: ≥95%
• Synonyms: 3-[2-[2-[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethyl-[3-[2-[2-[(2-methylpropan-2-yl)oxycarbonylamino]ethoxy]ethoxy]propanoyl]amino]ethoxy]ethoxy]ethoxy]propanoic acid
• InChI: InChI=1S/C29H55N5O13/c1-29(2,3)47-28(38)31-6-12-41-18-16-39-10-4-26(35)34(8-14-43-20-24-45-22-17-40-11-5-27(36)37)9-15-44-21-25-46-23-19-42-13-7-32-33-30/h4-25H2,1-3H3,(H,31,38)(H,36,37)
• InChIKey: KGAMPVINRLXGCH-UHFFFAOYSA-N
• SMILES: CC(C)(C)OC(=O)NCCOCCOCCC(=O)N(CCOCCOCCOCCC(=O)O)CCOCCOCCOCCN=[N+]=[N-]

N-(Azido-PEG3)-N-(PEG2-NH-Boc)-PEG3-acid(CAT: I016534) is a multifunctional heterobifunctional PEG linker designed for advanced bioconjugation strategies. It incorporates three distinct reactive groups: an azide for copper-catalyzed or strain-promoted click chemistry, a Boc-protected amine that can be selectively deprotected for subsequent coupling, and a terminal carboxylic acid for amide bond formation. The PEG3 and PEG2 spacers improve solubility, flexibility, and reduce steric hindrance, ensuring efficient conjugation across diverse biomolecules. This reagent is particularly valuable for site-specific labeling, drug delivery systems, and multifunctional probe construction, enabling orthogonal conjugation strategies in chemical biology, diagnostics, and targeted therapeutic development.