N-(Azido-PEG3)-N-Boc-PEG4-Boc

• CAT Number: I015899
• CAS Number: 2112731-94-7
• Molecular Formula: C28H54N4O11
• Molecular Weight: 622.75
• Purity: ≥95%
• Synonyms: tert-butyl 3-[2-[2-[2-[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethyl-[(2-methylpropan-2-yl)oxycarbonyl]amino]ethoxy]ethoxy]ethoxy]ethoxy]propanoate
• InChI: InChI=1S/C28H54N4O11/c1-27(2,3)42-25(33)7-11-35-15-19-39-23-24-41-22-18-38-14-10-32(26(34)43-28(4,5)6)9-13-37-17-21-40-20-16-36-12-8-30-31-29/h7-24H2,1-6H3
• InChIKey: SIZKOCYNJSTOPM-UHFFFAOYSA-N
• SMILES: CC(C)(C)OC(=O)CCOCCOCCOCCOCCN(CCOCCOCCOCCN=[N+]=[N-])C(=O)OC(C)(C)C

N-(Azido-PEG3)-N-Boc-PEG4-Boc（Cat No.:I015899）is a multifunctional PEG derivative featuring an azide group on a PEG₃ spacer and two Boc-protected amines linked through a PEG₄ chain. The azide moiety enables efficient bioorthogonal click chemistry, such as copper-catalyzed or strain-promoted cycloadditions, allowing site-specific conjugation under mild conditions. The Boc-protected amines can be deprotected to yield reactive primary amines for coupling with carboxyls, NHS esters, or aldehydes. The PEG spacers improve solubility, flexibility, and biocompatibility, while minimizing steric hindrance. This reagent is valuable for bioconjugation, crosslinking, and advanced drug delivery research.