N-(Azido-PEG3)-N-Biotin-PEG4-methyl ester

• CAT Number: I014502
• CAS Number: 2100306-76-9
• Molecular Formula: C30H54N6O11S
• Molecular Weight: 706.85
• Purity: ≥95%
• Synonyms: methyl 3-[2-[2-[2-[2-[5-[(3aR,4R,6aS)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoyl-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethyl]amino]ethoxy]ethoxy]ethoxy]ethoxy]propanoate
• InChI: InChI=1S/C30H54N6O11S/c1-40-28(38)6-10-41-14-18-45-22-23-47-21-17-44-13-9-36(8-12-43-16-20-46-19-15-42-11-7-32-35-31)27(37)5-3-2-4-26-29-25(24-48-26)33-30(39)34-29/h25-26,29H,2-24H2,1H3,(H2,33,34,39)/t25-,26-,29-/m1/s1
• InChIKey: ZZZFELOBFYPAJE-WWPJHQMMSA-N
• SMILES: COC(=O)CCOCCOCCOCCOCCN(CCOCCOCCOCCN=[N+]=[N-])C(=O)CCCC[C@@H]1[C@H]2[C@@H](CS1)NC(=O)N2

N-(Azido-PEG3)-N-Biotin-PEG4-methyl ester（Cat No.:I014502）is a multifunctional PEGylated biotin derivative featuring an azide group, a biotin moiety, and a terminal methyl ester, connected via PEG₃ and PEG₄ linkers. The azide group enables highly selective “click” chemistry through copper-catalyzed or strain-promoted cycloadditions, while the biotin unit allows strong, specific binding to streptavidin or avidin systems. The PEG linkers enhance solubility, reduce steric hindrance, and improve biocompatibility. The methyl ester provides synthetic versatility for further derivatization. This reagent is ideal for bioconjugation, affinity assays, targeted delivery, and biomolecular labeling.