N-(Azido-PEG2)-N-Boc-PEG4-NHS ester

• CAT Number: I015904
• CAS Number: 2093153-95-6
• Molecular Formula: C26H45N5O12
• Molecular Weight: 619.66
• Purity: ≥95%
• Synonyms: (2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethyl-[(2-methylpropan-2-yl)oxycarbonyl]amino]ethoxy]ethoxy]ethoxy]ethoxy]propanoate
• InChI: InChI=1S/C26H45N5O12/c1-26(2,3)42-25(35)30(8-12-38-16-15-37-11-7-28-29-27)9-13-39-17-19-41-21-20-40-18-14-36-10-6-24(34)43-31-22(32)4-5-23(31)33/h4-21H2,1-3H3
• InChIKey: JLYRAESBBJMWBK-UHFFFAOYSA-N
• SMILES: CC(C)(C)OC(=O)N(CCOCCOCCN=[N+]=[N-])CCOCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O

N-(Azido-PEG2)-N-Boc-PEG4-NHS ester（Cat No.:I015904）is a heterobifunctional PEG derivative featuring an azide group on a PEG₂ spacer, a Boc-protected amine, and an active NHS ester linked through a PEG₄ chain. The azide moiety enables efficient bioorthogonal click chemistry, such as copper-catalyzed or strain-promoted cycloadditions, while the NHS ester reacts rapidly with primary amines to form stable amide bonds. The Boc-protected amine can be deprotected for additional functionalization. PEG linkers enhance solubility, flexibility, and biocompatibility. This reagent is valuable in bioconjugation, crosslinking, surface modification, and drug delivery applications.