N-(Azido-PEG2)-N-Boc-PEG3-NHS ester

• CAT Number: I015905
• CAS Number: 2093153-85-4
• Molecular Formula: C24H41N5O11
• Molecular Weight: 575.61
• Purity: ≥95%
• Synonyms: (2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethyl-[(2-methylpropan-2-yl)oxycarbonyl]amino]ethoxy]ethoxy]ethoxy]propanoate
• InChI: InChI=1S/C24H41N5O11/c1-24(2,3)39-23(33)28(8-12-36-16-15-35-11-7-26-27-25)9-13-37-17-19-38-18-14-34-10-6-22(32)40-29-20(30)4-5-21(29)31/h4-19H2,1-3H3
• InChIKey: LICLIIAXFJFOMD-UHFFFAOYSA-N
• SMILES: CC(C)(C)OC(=O)N(CCOCCOCCN=[N+]=[N-])CCOCCOCCOCCC(=O)ON1C(=O)CCC1=O

N-(Azido-PEG2)-N-Boc-PEG3-NHS ester（Cat No.:I015905）is a multifunctional PEG derivative featuring an azide group on a PEG₂ spacer, a Boc-protected amine, and an NHS ester attached via a PEG₃ linker. The azide moiety enables efficient bioorthogonal click chemistry, such as copper-catalyzed or strain-promoted cycloadditions, for site-specific conjugation. The NHS ester couples rapidly with primary amines, forming stable amide bonds, while the Boc-protected amine can be deprotected for further modification. The PEG linkers enhance solubility, flexibility, and biocompatibility, making this reagent valuable for bioconjugation, crosslinking, nanoparticle engineering, and drug delivery research.