N-Arachidonyl maleimide

• CAT Number: I011659
• CAS Number: 876305-42-9
• Molecular Formula: C24H35NO2
• Molecular Weight: 369.54
• Purity: ≥95%
• Synonyms: 1-[(5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenyl]pyrrole-2,5-dione
• InChI: InChI=1S/C24H35NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-22-25-23(26)20-21-24(25)27/h6-7,9-10,12-13,15-16,20-21H,2-5,8,11,14,17-19,22H2,1H3/b7-6-,10-9-,13-12-,16-15-
• InChIKey: GZNZRHSGGQUYAP-DOFZRALJSA-N
• SMILES: CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCCN1C(=O)C=CC1=O

N-Arachidonyl maleimide（Cat No.:I011659）is a selective and irreversible inhibitor of protein kinase C (PKC), derived from arachidonic acid conjugated with maleimide. By covalently modifying cysteine residues within PKC, it disrupts kinase activity and downstream signaling pathways involved in cell proliferation, apoptosis, and inflammation. This compound is widely used in biochemical and pharmacological studies to probe PKC-dependent processes, including synaptic plasticity, cancer progression, and immune regulation. N-Arachidonyl maleimide also serves as a valuable tool for dissecting lipid–protein interactions and the roles of bioactive lipids in cellular signaling.