N-Acetyl-Ser-Asp-Lys-Pro acetate

For research use only. Not for therapeutic Use.

  • CAT Number: I044771
  • Molecular Formula: C22H37N5O11
  • Molecular Weight: 547.56
  • Purity: ≥95%
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N-Acetyl-Ser-Asp-Lys-Pro acetate(Cat No.:I044771)is a synthetic tetrapeptide corresponding to the N-terminal sequence of the AcSDKP motif, a naturally occurring peptide derived from thymosin β4. It is known for its anti-fibrotic and anti-proliferative properties, particularly in cardiovascular and renal research. This peptide inhibits hematopoietic stem cell proliferation and is regulated by angiotensin-converting enzyme (ACE), making it a focus of interest in studies of tissue remodeling and fibrosis. Supplied as an acetate salt for improved handling and solubility, it is widely used in biomedical research targeting fibrosis, inflammation, and regenerative processes.


Synonyms

(2S)-1-[(2S)-2-[[(2R)-2-[[(2S)-2-acetamido-3-hydroxypropanoyl]amino]-3-carboxypropanoyl]amino]-6-aminohexanoyl]pyrrolidine-2-carboxylic acid;acetic acid

Molecular Formula C22H37N5O11
Purity ≥95%
IUPAC Name (2S)-1-[(2S)-2-[[(2R)-2-[[(2S)-2-acetamido-3-hydroxypropanoyl]amino]-3-carboxypropanoyl]amino]-6-aminohexanoyl]pyrrolidine-2-carboxylic acid;acetic acid
InChI InChI=1S/C20H33N5O9.C2H4O2/c1-11(27)22-14(10-26)18(31)24-13(9-16(28)29)17(30)23-12(5-2-3-7-21)19(32)25-8-4-6-15(25)20(33)34;1-2(3)4/h12-15,26H,2-10,21H2,1H3,(H,22,27)(H,23,30)(H,24,31)(H,28,29)(H,33,34);1H3,(H,3,4)/t12-,13+,14-,15-;/m0./s1
InChIKey IYSLFKMYLHUWSA-UOIZBMALSA-N
SMILES CC(=O)N[C@@H](CO)C(=O)N[C@H](CC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)O.CC(=O)O
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