N-(8-Amino-6-fluoro-5-methyl-1-oxo-1,2,3,4-tetrahydronaphthalen-2-yl)acetamide

• CAT Number: L013533
• CAS Number: 182182-31-6
• Molecular Formula: C13H15FN2O2
• Molecular Weight: 250.27
• Purity: ≥95%
• IUPAC Name: N-(8-amino-6-fluoro-5-methyl-1-oxo-3,4-dihydro-2H-naphthalen-2-yl)acetamide
• InChI: InChI=1S/C13H15FN2O2/c1-6-8-3-4-11(16-7(2)17)13(18)12(8)10(15)5-9(6)14/h5,11H,3-4,15H2,1-2H3,(H,16,17)
• InChIKey: SEFPQWAVZCZXTK-UHFFFAOYSA-N
• SMILES: CC1=C(C=C(C2=C1CCC(C2=O)NC(=O)C)N)F

N-(8-Amino-6-fluoro-5-methyl-1-oxo-1,2,3,4-tetrahydronaphthalen-2-yl)acetamide(CAT: L013533) is an aromatic-fused bicyclic compound featuring a tetrahydronaphthalene core substituted with amino, fluoro, and methyl groups, along with an acetamide moiety. This multifunctional structure provides both hydrophilic and hydrophobic regions, enhancing its potential for biological activity. It is commonly investigated as an intermediate or active scaffold in medicinal chemistry, particularly in the development of enzyme inhibitors, receptor modulators, or anti-inflammatory agents. The presence of fluorine can improve metabolic stability and binding affinity, while the acetamide group supports hydrogen bonding interactions, making it a promising building block for drug discovery and structure–activity relationship (SAR) studies.