N-(4-fluoro-2-methoxy-5-nitrophenyl)-4-(1-methyl-1H-indol-3-yl)pyrimidin-2-amine

• CAT Number: L028776
• CAS Number: 1421372-94-2
• Molecular Formula: C20H16FN5O3
• Molecular Weight: 393.41
• Purity: ≥95%
• IUPAC Name: N-(4-fluoro-2-methoxy-5-nitrophenyl)-4-(1-methylindol-3-yl)pyrimidin-2-amine
• InChI: InChI=1S/C20H16FN5O3/c1-25-11-13(12-5-3-4-6-17(12)25)15-7-8-22-20(23-15)24-16-10-18(26(27)28)14(21)9-19(16)29-2/h3-11H,1-2H3,(H,22,23,24)
• InChIKey: SZTYQQYYIMVETL-UHFFFAOYSA-N
• SMILES: CN1C=C(C2=CC=CC=C21)C3=NC(=NC=C3)NC4=CC(=C(C=C4OC)F)[N+](=O)[O-]

N-(4-fluoro-2-methoxy-5-nitrophenyl)-4-(1-methyl-1H-indol-3-yl)pyrimidin-2-amine(CAT: L028776) is a structurally complex heteroaromatic compound designed for use in medicinal chemistry and drug discovery. It features a pyrimidine core substituted with a 1-methylindole moiety and a fluoro-methoxy-nitrophenyl group, offering both electron-donating and electron-withdrawing functionalities. This configuration supports interactions with biological targets such as kinases, receptors, or enzymes, making it a promising scaffold in the development of anticancer, anti-inflammatory, or CNS-active agents. The nitrophenyl substitution enhances bioactivity potential, while the indole ring contributes to receptor binding affinity. It is particularly valuable in structure–activity relationship (SAR) studies and high-throughput screening for novel therapeutic leads.