N-[4-(4-Fluorophenyl)-5-hydroxymethyl-6-isopropylpyrimidin-2-yl]-N-methylmethanesulfonamide

• CAT Number: R047175
• CAS Number: 147118-36-3
• Molecular Formula: C16H20FN3O3S
• Molecular Weight: 353.41
• Purity: ≥95%
• Synonyms: 5-(Hydroxymethyl)-4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidine; 4-(4-Fluorophenyl)-6-isopropyl-2-[(N-methyl-n-methylsulfonyl)amino]?pyrimidine-5-yl-metrhanol
• Storage: Room temperature
• IUPAC Name: N-[4-(4-fluorophenyl)-5-(hydroxymethyl)-6-propan-2-ylpyrimidin-2-yl]-N-methylmethanesulfonamide
• InChI: InChI=1S/C16H20FN3O3S/c1-10(2)14-13(9-21)15(11-5-7-12(17)8-6-11)19-16(18-14)20(3)24(4,22)23/h5-8,10,21H,9H2,1-4H3
• InChIKey: MSDYDUNHTAYBHV-UHFFFAOYSA-N
• SMILES: CC(C)C1=NC(=NC(=C1CO)C2=CC=C(C=C2)F)N(C)S(=O)(=O)C

N-[4-(4-Fluorophenyl)-5-hydroxymethyl-6-isopropylpyrimidin-2-yl]-N-methylmethanesulfonamide（Cat No.:R047175）is a complex sulfonamide-containing pyrimidine derivative known for its role as an intermediate or active compound in pharmaceutical research. The molecule features a substituted pyrimidine ring bearing a 4-fluorophenyl, hydroxymethyl, and isopropyl group, enhancing its lipophilicity and receptor binding potential. The N-methylmethanesulfonamide moiety contributes to aqueous solubility and biological activity, often associated with enzyme inhibition or receptor modulation. This compound is structurally related to known dihydroorotate dehydrogenase (DHODH) inhibitors and may be explored for antiviral, anticancer, or immunomodulatory applications in drug discovery.