N-[4-(4-Fluorophenyl)-5-formyl-6-(1-methylethyl)-2-pyrimidinyl]-N-methyl-methanesulfonamide

• CAT Number: R049846
• CAS Number: 147118-37-4
• Molecular Formula: C16H18FN3O3S
• Molecular Weight: 351.39
• Purity: ≥95%
• Synonyms: 4-(4-Fluorophenyl)-6-isopropyl-2-(N-methyl-N-methylsulfonylamino)-5-pyrimidinecarboxaldehyde; N-[4-(4-Fluorophenyl)-5-formyl-6-(1-methylethyl)-2-pyrimidinyl]-N-methylmethanesulfonamide
• Storage: Store at RT
• IUPAC Name: N-[4-(4-fluorophenyl)-5-formyl-6-propan-2-ylpyrimidin-2-yl]-N-methylmethanesulfonamide
• InChI: InChI=1S/C16H18FN3O3S/c1-10(2)14-13(9-21)15(11-5-7-12(17)8-6-11)19-16(18-14)20(3)24(4,22)23/h5-10H,1-4H3
• InChIKey: WOCOTUDOVSLFOB-UHFFFAOYSA-N
• SMILES: CC(C)C1=NC(=NC(=C1C=O)C2=CC=C(C=C2)F)N(C)S(=O)(=O)C

N-[4-(4-Fluorophenyl)-5-formyl-6-(1-methylethyl)-2-pyrimidinyl]-N-methyl-methanesulfonamide（Cat No.:R049846）is a complex sulfonamide-containing heterocycle, featuring a pyrimidine core substituted with a 4-fluorophenyl group, a formyl (aldehyde) group, and an isopropyl moiety. The sulfonamide nitrogen is methylated and linked to a methanesulfonyl group, enhancing its chemical stability and polarity. This compound is typically used as a pharmaceutical intermediate or as a lead scaffold in drug discovery, particularly for designing enzyme inhibitors or receptor antagonists. Its multiple functional groups provide diverse reactivity and binding interactions, making it suitable for medicinal chemistry and structure–activity relationship (SAR) studies.