N-3-Oxo-tetradecanoyl-L-homoserine lactone

• CAT Number: M127097
• CAS Number: 177158-19-9
• Molecular Formula: C18H31NO4
• Molecular Weight: 325.44
• Purity: ≥95%
• Synonyms: 3-oxo-N-[(3S)-2-oxooxolan-3-yl]tetradecanamide
• InChI: InChI=1S/C18H31NO4/c1-2-3-4-5-6-7-8-9-10-11-15(20)14-17(21)19-16-12-13-23-18(16)22/h16H,2-14H2,1H3,(H,19,21)/t16-/m0/s1
• InChIKey: YQFJJDSGBAAUPW-INIZCTEOSA-N
• SMILES: CCCCCCCCCCCC(=O)CC(=O)NC1CCOC1=O

N-3-Oxo-tetradecanoyl-L-homoserine lactone (Cat No.: M127097) is a long-chain acyl-homoserine lactone (AHL) quorum sensing signal molecule used by Gram-negative bacteria to coordinate population-dependent behaviors. It functions by binding to LuxR-type receptors, regulating gene expression involved in biofilm formation, virulence, motility, and symbiosis. As a key autoinducer in quorum sensing research, 3-oxo-C14-HSL provides insights into bacterial communication, pathogenicity, and interspecies interactions. It is widely employed in microbiology and drug discovery to study anti-virulence strategies, quorum quenching, and microbial community regulation.

Reference

[1]. Adss S, et al. Priming Soybean cv. Primus Leads to Successful Systemic Defense Against the Root-Lesion Nematode, Pratylenchus penetrans. Front Plant Sci. 2021;12:651943. Published 2021 May 12.
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