N-3-Oxo-hexadecanoyl-L-Homoserine lactone

• CAT Number: R060965
• CAS Number: 925448-37-9
• Molecular Formula: C20H35NO4
• Molecular Weight: 353.50
• Purity: ≥95%
• Synonyms: 3-oxo-N-[(3S)-2-oxooxolan-3-yl]hexadecanamide
• InChI: InChI=1S/C20H35NO4/c1-2-3-4-5-6-7-8-9-10-11-12-13-17(22)16-19(23)21-18-14-15-25-20(18)24/h18H,2-16H2,1H3,(H,21,23)/t18-/m0/s1
• InChIKey: YZBAMTUXUHIYCQ-SFHVURJKSA-N
• SMILES: CCCCCCCCCCCCCC(=O)CC(=O)NC1CCOC1=O

N-3-Oxo-hexadecanoyl-L-homoserine lactone (Cat No.: R060965) is a long-chain acyl-homoserine lactone quorum sensing signal molecule produced by Gram-negative bacteria. It functions as an autoinducer in cell-to-cell communication, regulating gene expression linked to virulence, biofilm formation, and host–pathogen interactions. This compound is widely used in microbiology and chemical biology research to study quorum sensing networks and bacterial community behavior. Due to its stability and specificity, N-3-oxo-C16-HSL is a valuable tool for investigating microbial signaling and developing quorum sensing–based antimicrobial strategies.

Reference

[1]. Gahan CG, et al. Interactions of Bacterial Quorum Sensing Signals with Model Lipid Membranes: Influence of Acyl Tail Structure on Multiscale Response. Langmuir. 2021;37(41):12049-12058.
[Content Brief]