• CAT Number: I010207
  • CAS Number: 78351-75-4
  • Molecular Formula: C20H14ClN3
  • Molecular Weight: 331.8
  • Purity: ≥95%
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MY-5445(Cat No.: I010207), is a highly specific inhibitor of cGMP phosphodiesterase PDE5, with a Ki value of 1.3 μM. Its inhibitory action extends to human platelet aggregation, making it valuable for antiplatelet and cardiovascular research. Moreover, MY-5445 serves as an ABCG2 transporter modulator, impacting the activity of this transporter involved in drug resistance mechanisms. This dual functionality hints at its potential in cancer research and treatment as an antiproliferative agent. MY-5445’s versatility positions it as a valuable compound for understanding and targeting various biological processes and pathways in both cardiovascular and cancer-related studies.

Catalog Number I010207
CAS Number 78351-75-4


Molecular Formula


Purity 95%
Target PDE
Solubility Soluble to 50 mM in DMSO and to 5 mM in ethanol
Storage Store at RT
IUPAC Name N-(3-chlorophenyl)-4-phenylphthalazin-1-amine
InChI InChI=1S/C20H14ClN3/c21-15-9-6-10-16(13-15)22-20-18-12-5-4-11-17(18)19(23-24-20)14-7-2-1-3-8-14/h1-13H,(H,22,24)

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