Mutant p53 modulator-1

• CAT Number: I043856
• CAS Number: 2746371-35-5
• Molecular Formula: C27H32F4N8O2
• Molecular Weight: 576.59
• Purity: ≥95%
• Synonyms: 1-tert-butyl-N-[[3-[4-[[(3S,4R)-3-fluoro-1-methylpiperidin-4-yl]amino]-1-(2,2,2-trifluoroethyl)indol-2-yl]-1,2,4-oxadiazol-5-yl]methyl]pyrazole-4-carboxamide
• InChI: InChI=1S/C27H32F4N8O2/c1-26(2,3)39-13-16(11-33-39)25(40)32-12-23-35-24(36-41-23)22-10-17-19(34-20-8-9-37(4)14-18(20)28)6-5-7-21(17)38(22)15-27(29,30)31/h5-7,10-11,13,18,20,34H,8-9,12,14-15H2,1-4H3,(H,32,40)/t18-,20+/m0/s1
• InChIKey: APGSTYOSWBCZAT-AZUAARDMSA-N
• SMILES: CC(C)(C)N1C=C(C=N1)C(=O)NCC2=NC(=NO2)C3=CC4=C(C=CC=C4N3CC(F)(F)F)N[C@@H]5CCN(C[C@@H]5F)C

Mutant p53 Modulator-1（Cat No.:I043856）is a small molecule designed to target and restore the function of mutant p53, a tumor suppressor protein commonly altered in various cancers. Mutations in p53 often result in the loss of its ability to regulate cell cycle and apoptosis, contributing to uncontrolled cell growth and cancer progression. By modulating mutant p53, this compound aims to reactivate its tumor-suppressing functions, inducing cancer cell death and inhibiting tumor growth. Mutant p53 Modulator-1 is being studied in preclinical research for its potential as a targeted therapeutic in cancer treatment.