Msr-blue

• CAT Number: I045002
• CAS Number: 2966537-39-1
• Molecular Formula: C11H10O3S
• Molecular Weight: 222.26
• Purity: ≥95%
• Synonyms: 4-methyl-7-methylsulfinylchromen-2-one
• InChI: InChI=1S/C11H10O3S/c1-7-5-11(12)14-10-6-8(15(2)13)3-4-9(7)10/h3-6H,1-2H3
• InChIKey: IFTHUDRVKVIXDN-UHFFFAOYSA-N
• SMILES: CC1=CC(=O)OC2=C1C=CC(=C2)S(=O)C

Msr-blue（Cat No.:I045002）is a selective, cell-permeable inhibitor that targets the methionine sulfoxide reductase (Msr) system, a key antioxidant enzyme complex involved in repairing oxidatively damaged proteins by reducing methionine sulfoxide back to methionine. By blocking Msr function, Msr-blue sensitizes cells to oxidative stress, making it a valuable research tool for investigating redox biology, oxidative damage pathways, and age-related or neurodegenerative diseases. This compound is particularly useful in studying mitochondrial oxidative stress and proteostasis, as well as evaluating therapeutic strategies that involve modulating cellular antioxidant defenses in disease models.